Table 1.
Free fatty acids | Controls | Pre-treated BC patients | Post-treated BC patients |
---|---|---|---|
C-14: 0 | 1.26 ± 0.96 | 1.30 ± 0.30 | 0.81 ± 0.44 |
C-15: 0 | ND | 0.57 ± 0.24 | ND |
C-16: 0 | 18.17 ± 5.06 | 23.0 ± 2.86* | 28.2 ± 2.47* |
C-18: 0 | 13.89 ± 3.56 | 21.8 ± 2.00* | 15.9 ± 1.76¶ |
C-14: 1 | 0.75 ± 0.49 | 1.86 ± 0.51 | 0.04 ± 0.01 |
C-16: 1 | 2.619 ± 1.37 | 1.85 ± 0.48 | 2.66 ± 0.96 |
C-18: 1 | 19.71 ± 2.276 | 27.3 ± 1.63* | 26.5 ± 2.01* |
C-18: 2 (n-6) | 29.14 ± 3.28 | 20.2 ± 1.65* | 19.84 ± 2.37* |
C-18: 3 (n-3) | 1.54 ± 0.79 | 1.21 ± 0.836* | 0.76 ± 0.40* |
C-20: 3 (n-6) | 0.65 ± 0.3 | 0.39 ± 0.19 | 0.6 ± 0.47 |
C-20: 4 (n-6) | 7.76 ± 2.40 | 1.09 ± 0.52* | 2.7 ± 1.55*¶ |
C-22: 6 (n-3) | 1.18 ± 0.79 | 0.47 ± 0.24 | 1.88 ± 1.74 |
C-18:0: C-18:1 | 0.719 ± 0.24 | 0.79 ± 0.06 | 0.605 ± 0.090 |
C-18:2: C-18:1 | 1.5 ± 0.28 | 0.074 ± 0.03 | 0.75 ± 0.118 |
C-18:3: C-18:1 | 0.071 ± 0.033 | 2.8 ± 0.97* | 0.008 ± 0.002*¶ |
n-3: n-6 | 7.4 ± 1.41 | 2.80 ± 1.01* | 3.43 ± 1.71*¶ |
Sat: unsat FA’s | 35.2 ± 6.05 | 25.0 ± 1.34* | 26.6 ± 3.47* |
D5 Desaturase | 21.2 ± 19.1 | 3.83 ± 3.4* | 7.84 ± 1.2 |
D6 Desaturase | 0.019 ± 0.009 | 0.03 ± 0.02 | 0.02 ± 0.013 |
Values represent mean ± standard deviation of triplicates. The different symbol on the same row indicates the Significant difference at p < 0.05. *p < 0.05 shows the comparison between pre and post treated BC patients with controls, ¶ p < 0.05 shows the comparison between pre-treated BC patients and post treated BC patients. Lauric acid (C12:0), Myristic acid (C14:1), myristoleic acid (C14:1), Pentadecyclic acid (C15:0), palmitic acid (C16:0), palmitoleic acid (C16:1), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2), α-linolenic acid (C18:3), C20:3 (Dihomo-γ-linolenic acid), arachidonic acid (C20:4) and docosahexaenoic acid (DHA (C22:6). D5 Desaturase was calculated as 20:4n-6/20:3n-6 ratio. D6 Desaturase was calculated as 20:3n-6/18:2n-6 ratio. Sat: unsat FA’s shows saturated and unsaturated fatty acids ratio