Table 3.
Treatment | Dose (mg/kg) | Body weight (BW) (g) | Liver weight (LW) (g) | LW/BW (%) |
---|---|---|---|---|
Control | - | 208.70 ± 5.55 | 5. 85 ± 0.29 | 2.80 ± 0.07 |
APAP treated rats | 219.50 ± 4.72 | 9.72 ± 0.15a | 4. 44 ± 0.43a | |
Silymarin + APAP | 200 | 200.00 ± 4.67 | 6.94 ± 0.24ab | 3.47 ± 0.11ab |
MEDL + APAP | 50 | 218.07 ± 3.19 | 7.83 ± 0.88ab | 3.59 ± 0.80ab |
250 | 224.10 ± 3.41 | 6.16 ± 0.51b | 2.75 ± 0.87b | |
500 | 218.64 ± 2.83 | 6.65 ± 0.87b | 3.04 ± 0.88b |
Values are expressed as means ± S.E.M. of six replicates
aSignificant different as compared to normal control, p < 0.05
bSignificant different as compared to negative control, p < 0.05