Table 4.

Effects of different treatments on serum liver biomarkers of experimental rats

Treatment	Dose (mg/kg)	ALT (U/L)	AST (U/L)	ALP (U/L)
Control	-	158.30 ± 2.86	95.13 ± 5.92	115.70 ± 6.99
APAP control (neg)		1714.00 ± 142.20a	2266.00 ± 340.40a	330.00 ± 42.35a
Silymarin +APAP (pos)	200	474.50 ± 82.17b	690.90 ± 146.60b	195.50 ± 11.06b
MEDL	50	225.90 ± 77.18b	309.50 ± 94.85b	252.20 ± 45.72
	250	479.00 ± 204.10b	1184.00 ± 564.30b	228.20 ± 36.76b
	500	445.10 ± 66.73b	786.60 ± 96.77b	350.30 ± 41.33

Values are expressed as means ± S.E.M. of six replicates

^aSignificant different as compared to normal control, p < 0.05

^bSignificant different as compared to negative control, p < 0.05