Table 3.
Association between TSH categories and total joint replacement (TJR) in the hip or knee due to osteoarthritis
| TSH (mU/L) | Persons (n) | Cases (n) | HRa | (95% CI) | HRb | (95% CI) | HRc | (95% CI) |
|---|---|---|---|---|---|---|---|---|
| <0.50 | 908 | 35 | 1.08 | (0.77–1.52) | 1.10 | (0.78–1.55) | 1.15 | (0.79–1.67) |
| 0.50–1.49 | 17675 | 635 | 0.95 | (0.84–1.06) | 1.10 | (0.98–1.23) | 1.10 | (0.97–1.25) |
| 1.5–2.49 | 13228 | 550 | 1 | Reference | 1 | Reference | 1 | Reference |
| 2.5–3.49 | 3773 | 169 | 1.03 | (0.87–1.22) | 0.88 | (0.74–1.05) | 0.88 | (0.73–1.06) |
| >3.5 | 2307 | 127 | 1.23 | (1.01–1.49) | 0.97 | (0.80–1.17) | 0.94 | (0.76–1.16) |
aUnadjusted
bAdjusted for age, sex, BMI and smoking
cAdjusted for age, sex, BMI, smoking, physical activity and diabetes