Table 6.
All trials | All trials excluding FMHS | Adequately controlled trials | Adequately controlled trials excluding SDHS | Inadequately controlled trials | |
---|---|---|---|---|---|
Major CHD Events | 0.87 (0.70-1.07) | 0.93 (0.77-1.11) | 1.06 (0.86-1.31) | 0.98 (0.83-1.16) | 0.64 (0.47-0.87) |
P = 0.19 | P = 0.40 | P = 0.59 | P = 0.80 | P = 0.004 | |
I2 = 60% | I2 = 48% | I2 = 46% | I2 = 17% | I2 = 38% | |
Total CHD Events | 0.80 (0.65-0.98) | 0.83 (0.67-1.03) | 1.02 (0.84-1.23) | 0.95 (0.83-1.09) | 0.60 (0.46-0.79) |
P = 0.03 | P = 0.10 | P = 0.85 | P = 0.45 | P = 0.0002 | |
I2 = 72% | I2 = 71% | I2 = 45% | I2 = 1% | I2 = 59% | |
CHD Mortality | 0.90 (0.70-1.17) | 0.98 (0.79-1.23) | 1.13 (0.91-1.40) | 1.04 (0.85-1.27) | 0.66 (0.54-0.81) |
P = 0.43 | P = 0.88 | P = 0.29 | P = 0.71 | P < 0.0001 | |
I2 = 65% | I2 = 39% | I2 = 19% | I2 = 0% | I2 = 11% | |
Total Mortality | 1.00 (0.90-1.10) | 0.99 (0.86-1.15) | 1.07 (0.90-1.26) | 1.03 (0.90-1.17) | 0.95 (0.82-1.10) |
P = 0.99 | P = 0.91 | P = 0.45 | P = 0.69 | P = 0.48 | |
I2 = 26% | I2 = 34% | I2 = 23% | I2 = 0% | I2 = 35% |
Data are in relative risk and then 95% confidence intervals in parentheses, with P values and I2 values below