Table 3.
Association between baseline systemic bone mineral density and progression of tibiofemoral cartilage defects
| Univariable analysis Odds ratio (95% CI) |
P | Multivariable analysisa
Odds ratio (95% CI) |
P | |
|---|---|---|---|---|
| Total body BMD | ||||
| Medial | 1.25 (0.80, 1.94) | 0.33 | 1.71 (0.94, 3.08) | 0.08 |
| Lateral | 1.19 (0.78, 1.81) | 0.42 | 1.45 (0.84, 2.50) | 0.18 |
| Spine BMD | ||||
| Medial | 1.38 (1.07, 1.77) | 0.01 | 1.45 (1.10, 1.91) | 0.01 |
| Lateral | 1.19 (0.94, 1.52) | 0.15 | 1.30 (1.00, 1.67) | 0.049 |
| Total hip BMD | ||||
| Medial | 1.33 (1.00, 1.75) | 0.05 | 1.63 (1.10, 2.41) | 0.02 |
| Lateral | 1.22 (0.93, 1.59) | 0.15 | 1.53 (1.08, 2.18) | 0.02 |
BMD (bone mineral density) was assessed in g/10 cm2 so that one unit change in BMD approximated one standard deviation change in BMD. aAdjusted for gender, baseline age, body mass index, strenuous physical activity, respective baseline tibial cartilage volume and bone area, and time between scans