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. 2017 May 19;17:344. doi: 10.1186/s12885-017-3345-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Clinical significance of XLF expression. a Genomic alteration frequency for XLF was calculated using cBioPortal [http://www.cbioportal.org] from the TCGA (193 patients) and AMC (231 patients) databases. Tumor types are indicated at the bottom and ordered by the frequency of samples harboring mutation, deletion, amplification and multiple alterations. The XLF mutation rate in HCC is highlighted. b Statistical comparison of XLF gene expression in tumor tissue between patients with HCC who underwent TACE (n = 31) and those who did not (n = 22). c Kaplan-Meier analysis of overall survival between patients with HCC with high and low expression of XLF, who all underwent TACE treatment. d Kaplan-Meier analysis of disease-free survival for patients with HCC as in c