Table 1.
PvRBSA mutations found by comparing the nucleotide and amino acid sequences of P. vivax VCG-I and Sal-1 strains
Changes in PvRBSA nucleotide sequence in Sal-I and VCG-I P. vivax strainsa | Changes in PvRBSA aa sequences in Sal-I and VCG-I P. vivax strainsa | Mutation |
---|---|---|
c.29A > G | p.Tyr10Cys | Non-synonymous |
c.391_411delCTAACAGGAAGTAATGAATCC | p.Leu131_Ser137delb | Deletion |
c.533 T > G | p.Phe178Cys | Non-synonymous |
c.796A > G | p.Lys266Gly | Non-synonymous |
c.797A > G | p.Lys266Gly | Non-synonymous |
c.801 T > A | p.Ser267Arg | Non-synonymous |
c.803A > C | p.Tyr268Ser | Non-synonymous |
c.808C > G | p.His270Asp | Non-synonymous |
c.845C > T | p.Pro282Leu | Non-synonymous |
c.1029 T > C | p.Lys343Lys | Synonymous |
c.1091G > C | p.Trp364Ser | Non-synonymous |
aNucleotide and amino acid positions are numbered according to the Sal-I reference strain sequence alignment with the VCG-I strain
bRelative location for a region having 4 identical tandem repeats from amino acid position 103 to 130 in the VCG-I strain