Table 2.
Clinical characteristics based on number of comorbid psychiatric disorders.
| All | Number of comorbid psychiatric disorders* | ||||
|---|---|---|---|---|---|
|
| |||||
| 0 | 1 | 2+ | |||
|
|
|||||
| N=302 | N=171 (57%) | N=60 (20%) | N=71 (24%) | ||
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | P-value | |
| Psychiatric symptoms | |||||
| QIDS-C16 (depression severity, range of 0–27) | 5.4 (3.1) | 4.6 (2.8) | 5.6 (2.6) | 6.9 (3.6) | < 0.0011 |
| CHRT-SR suicide propensity (items 1–11, range 0–44) | 8.6 (6.9) | 7.1 (6.0) | 8.5 (6.7) | 12.3 (7.8) | < 0.0011 |
| CHRT-SR suicide risk (items 12–14, range 0–12) | 0.5 (1.2) | 0.4 (1.0) | 0.4 (1.0) | 0.8 (1.6) | 0.0232 |
| Health related quality of life and function | |||||
| SCQ (medical disorder burden, range 1–54) | 1.2 (1.9) | 0.9 (1.7) | 1.6 (2.3) | 1.5 (2.1) | 0.0113 |
| SF-36 mental functioning (range of 0–100) | 42.5 (13.7) | 46.7 (12.9) | 40.1 (12.0) | 34.4 (12.9) | < 0.0004 |
| SF-36 physical functioning (range of 0–100) | 55.0 (7.3) | 55.4 (6.4) | 54.4 (8.1) | 54.4 (8.7) | 0.530 |
| Q-LES-Q (life satisfaction/enjoyment, range of 0–100)) | 68.6 (16.3) | 72.2 (15.7) | 67.0 (14.3) | 61.6 (17.1) | < 0.0012 |
| P-FIBS (pain, range of 0–32) | 5.0 (6.9) | 3.5 (5.5) | 6.4 (7.4) | 7.5 (8.4) | < 0.0013 |
| ASI employment subscale | 0.7 (0.3) | 0.7 (0.3) | 0.8 (0.3) | 0.7 (0.3) | 0.060 |
| ASI family subscale | 0.2 (0.2) | 0.2 (0.2) | 0.2 (0.2) | 0.3 (0.2) | < 0.0011 |
| ASI legal subscale | 0.1 (0.2) | 0.1 (0.2) | 0.1 (0.2) | 0.2 (0.2) | 0.570 |
| ASI medical subscale | 0.2 (0.3) | 0.1 (0.2) | 0.2 (0.3) | 0.2 (0.3) | 0.0033 |
| ASI psychiatric subscale | 0.3 (0.2) | 0.2 (0.2) | 0.3 (0.2) | 0.5 (0.2) | < 0.0014 |
| CPFQ (cognitive and physical functioning, range of 7–42) | 17.9 (6.3) | 16.4 (5.7) | 19.0 (6.5) | 20.5 (6.4) | < 0.0013 |
SD-standard deviation, QIDS-C16-Quick Inventory of Depressive Symptoms-Clinician Rated, CHRT-SR-Concise Health Risk Tracking-Self Report, SCQ-Self-Administered Comorbidity Questionnaire, SF-36-Short Form Health Survey, Q-LES-Q-Quality of Life Enjoyment and Satisfaction Questionnaire Short Form, P-FIBS-Pain Frequency, Intensity, and Burden Scale, ASI-Addiction Severity Index Lite, CPFQ-MGH Cognitive and Physical Functioning Questionnaire
Diagnoses based on the MINI International Neuropsychiatric Interview and include major depression (n=68), dysthymia (n=22,) mania (n=15), hypomania (n=7), panic disorder (n=17), social phobia(n=32), obsessive-compulsive disorder, (n=18), post-traumatic stress disorder (n=28), generalized anxiety (n=46), bulimia (n=6).
2+ disorders significantly different from 1 and from 0 disorders (Tukey HSD Test, p<0.05)
2+ disorders significantly different from 0 disorder (Tukey HSD Test, p<0.05)
2+ disorders significantly different than 0 disorder, 1 disorder significantly different than 0 disorder (Tukey HSD Test, p<0.05)
2+, 1, and 0 disorder are all significantly different (Tukey HSD Test, p<0.05)