Figure 2.

Cellular location and enzymatic activity of P. aeruginosa Nuh. Periplasmic Nuh produces ribose and adenine from the hydrolysis of adenosine. Inosine may serve as an alternative substrate that is converted into ribose and hypoxanthine (not shown). Specific transporters take up the products into the cytoplasm. The proteins involved in nucleoside transport across the outer membrane (if any) and in adenine nucleobase transport across the inner membrane have not been identified in P. aeruginosa.