TABLE 2.
Obstructive sleep apnoea severity in 13 patients who slept supine on both study nights
| Placebo | Desipramine | p-value | |
|---|---|---|---|
| AHI NREM supine events·h−1 sleep | 42.0 (30.8) | 34.3 (54.9) | >0.5 |
| ArI NREM supine events·h−1 sleep | 54.6 (50.3) | 56.2 (35.2) | >0.5 |
| % hypopneas | 78 (37) | 94 (16) | 0.11 |
| ODI NREM supine events·h−1 sleep | 28 (23) | 4 (48) | >0.5 |
| Nadir SaO2 % | 90 (3.8) | 92 (3.8) | 0.02 |
Data are presented as median (interquartile range), unless otherwise stated. AHI: apnoea-hypopnoea index; NREM: non-rpaid eye movement sleep; ArI: arousal index; ODI: oxygen desaturation index; SaO2: arterial oxygen saturation. Individual data are shown in the supplementary data. One subject was excluded from this analysis as he could not sleep while supine on the placebo night.