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. 2016 Oct 12;42(6):1210–1219. doi: 10.1038/npp.2016.186

Figure 1.

Figure 1

GBCr alterations in MDD at baseline and following ketamine treatment. Clusters mark brain regions with significant GBCr reduction (blue) or increase (red–yellow) in MDD compared with HC prior to ketamine treatment (a) and 24 h after intravenous infusion of ketamine (b) (whole-brain voxel-wise independent t-test with corrected α<0.05). The prefrontal cortex region is labeled with a black line. HC, healthy controls; GBCr, global brain connectivity with global signal regression; MDD, major depressive disorder. A full color version of this figure is available at the Neuropsychopharmacology journal online.