Table 3. Subpopulation proportions delineated by FSC/SSC (central), FSC/SSC (extended) strategies in normal pregnancy and URM.
Marker | Cell | FSC/SSC (central) | FSC/SSC (extend) | ||
---|---|---|---|---|---|
Normal pregnancy | URM | Normal pregnancy | URM | ||
CD3+CD56– | T | 28.4 ± 3.2 | 27.5 ± 3.1 | 21.5 ± 2.4 | 23.3 ± 2.7 |
CD3–CD56brightCD16– | dNK | 39.2 ± 4.6 | 46.6 ± 4.6 | 45.4 ± 3.7 | 49.6 ± 3.7 |
CD3–CD56brightCD16–/CD3+CD56– | dNK/T | 1.5 ± 0.5 | 1.8 ± 0.2 | 2 ± 0.2 | 2.0 ± 0.2 |
CD3+CD56+ | NKT-like | 6.9 ± 0.9 | 6.2 ± 1.5 | 7.5 ± 0.7 | 7.4 ± 1.5 |
CD3+CD4+CD8– | Th | 53.9 ± 2.1 | 47.9 ± 1.9 | 54.0 ± 2.0 | 48.3 ± 1.7 |
CD3+CD4–CD8+ | Tc | 27.9 ± 1.6 | 28.5 ± 1.9 | 28.1 ± 1.5 | 26.7 ± 1.7 |
CD3+CD4+CD8–/CD3+CD4–CD8+ | Th/Tc | 2 ± 0.2 | 1.8 ± 0.2 | 2.1 ± 0.1 | 1.9 ± 0.2 |
CD3+CD4+CD8–IFN-γ+IL-4– | Th1 | 37.4 ± 2.5 | 43.9 ± 1.8 | 34.8 ± 1.9 | 42.7 ± 1.7 |
CD3+CD4+CD8–IFN-γ–IL-4+ | Th2 | 1.2 ± 0.3 | 0.4 ± 0.1 | 0.8 ± 0.2 | 0.9 ± 0.2 |
CD3+CD4+CD8–IFN-γ+IL-4+ | Th DP* | 4.8±0.7 | 3.8 ± 0.9 | 3.2 ± 0.4 | 5.6 ± 1.1 |
CD3+CD4+CD8–IFN-γ+IL-4– /CD3+CD4+CD8–IFN-γ–IL-4+ | Th1/Th2 | 74.3 ± 14.6 | 167.0 ± 11.5 | 103.4 ± 23.0 | 82.5 ± 15.2 |
CD3+CD4–CD8+IFN-γ+IL-4– | Tc1 | 49.5 ± 2.8 | 57.1±3.6 | 43.7±2.4 | 56.8 ± 2.9 |
CD3+CD4–CD8+IFN-γ–IL-4+ | Tc2 | 1.4 ± 0.3 | 2.0±1.4 | 3.9±0.9 | 2.1 ± 0.8 |
CD3+CD4–CD8+IFN-γ+IL-4+ | Tc DP* | 2.9 ± 0.5 | 1.6 ± 0.4 | 3.3 ± 0.5 | 3.1 ± 0.6 |
CD3+CD4−CD8+IFN-γ+IL-4−/CD3+CD4– CD8+IFN-γ–IL-4+ | Tc1/Tc2 | 83.4 ± 18.5 | 113.7 ± 11.9 | 28.0 ± 5.6 | 39.4 ± 7.8 |
CD3–CD56brightCD16–IFN-γ+IL-4– | dNK1 | 9.2 ± 1.3 | 8.1 ± 2.0 | 5.2 ± 1.1 | 9.9 ± 2.2 |
CD3–CD56brightCD16–IFN-γ–IL-4+ | dNk2 | 3.2 ± 0.7 | 0.7 ± 0.2 | 8.4 ± 1.4 | 4.0 ± 0.7 |
CD3–CD56brightCD16–IFN-γ+IL-4+ | dNK DP* | 0.2 ± 0.1 | 0.01 ± 0.006 | 0.3 ± 0.1 | 0.3 ± 0.1 |
CD3–CD56brightCD16–IFN-γ+IL-4 – /CD3–CD56brightCD16–IFN-γ–IL-4+ | dNk1/dNK2 | 11.2 ± 3.2 | 72.1 ± 12.1 | 3.5 ± 1.6 | 5.7 ± 2.8 |
*DP represents double positive cell.