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. Author manuscript; available in PMC: 2018 May 15.
Published in final edited form as: J Immunol. 2017 Apr 12;198(10):3919–3926. doi: 10.4049/jimmunol.1601404

Figure 7. Enforced expression of TCF1 regardless of its capacity to interact with β-catenin in R24Tg T cells led to further decrease in IL-4 production and GATA3 expression.

Figure 7

FACS analysis of (A) IL-4 production and (B) GATA3 expression in GFP+ R24Tg CD4+ T cells transduced with control vector or vectors expressing either L-TCF1 or S-TCF1 with a GFP reporter under Th2- polarizing conditions. n-fold changes (on the basis of corresponding WT controls) of IL-4+ cell frequencies or GATA3 MFI in GFP+ R24Tg CD4+ T cells were shown on the right panels. Data are representative of at least four independent experiments (n = 4–6). *p<0.05.