Table 1. Prior experience with PE in pHUS.

Study	Case	Identification of pHUS	Exchange	Outcome
Waters et al. 2007 [5]	43 patients with pHUS, ages 5 – 39 months, 6 treated with PE	Not specified (pneumococcus identified in 34 of 43 cases, T-activation identified in 36 of 37 cases	3 patients with albumin, 2 with FFP, 1 unknown	All survived, 1 patient in albumin group with chronic kidney disease (CKD), 1 patient in FFP group with neurologic deficit and mild CKD
Hopkins et al. 2008 [7]	2-year-old male	Blood culture positive for S. pneumoniae, T-activation	Albumin	Complete recovery, remained well at 7 month follow-up
Petras et al. 2012 [8]	4-year-old female	Chest tube drainage positive for S. pneumoniae, T-activation	Albumin	Complete recovery, no sequelae at 16 month follow-up
Our case	2-year-old male	Pneumonia, T-activation, urine antigen positive	Albumin	Complete recovery