Table 1. Laboratory parameters and therapeutic interventions.
| Case 1 | Case 2 | |
|---|---|---|
| Vital signs | ||
| Pulse (beats/min) | 114 | 69 |
| BP (mmHg) | 127/92 | 134/58 |
| Laboratory parameters | ||
| Baseline SCr (0.5 – 1.4 mg/dL) | NA | 0.8 |
| Admission SCr (mg/dL) | 0.9 | 0.9 |
| Peak SCr (mg/dL) | 1.1 | 0.9 |
| Hemoglobin (11.6 – 14.6 g/dL) | 14.3 | 13.8 |
| Platelets (156 – 369 k/cumm) | 262 | 211 |
| Pre-HDaPTT (22.7 – 35.6sec) | 38.2 | 36.5 |
| Post-HD aPTT (sec) | 33.2 | 26.3 |
| Pre-HD TT (16 – 22 sec) | >150 | >150 |
| Post-HD TT (sec) | 60 | 39.3 |
| Pre-HD INR (0.8 – 1.2) | 1.4 | 1.2 |
| Post-HD INR | 1.0 | 0.9 |
| Pre-HD dabigatran (ng/dL) | 123 | 41 |
| Post-HD dabigatran (ng/dL) | < 40 | <40 |
| Therapeutic interventions | ||
| Platelets (units) | None | 1 |
| rFactor VII (mg) | 3 | 2.5 |
| HD duration (hours) | 4 | 4 |
| QD (mL/min) | 800 | 800 |
| QB (mL/min) | 400 | 400 |
| HD catheter | Left femoral | Right femoral |
BP = blood pressure; SCr = serum creatinine; HD = hemodialysis; aPTT = activated partial thromboplastin time; PT = prothrombin time; INR = international normalization ratio; TT = thrombin clotting time; rFactor VII = recombinant Factor VII; QD = dialysate flow rate; QB = blood flow rate; NA = not available.