Table 1. Demographics, haematological and peripheral iron measures.
| Demographics | Control Group | Cocaine Group |
Group Comparison |
||
|---|---|---|---|---|---|
| Mean (±s.d.) | Mean (±s.d.) | t or U | P-value | ||
| Gender ratio (male: female) | 40: 3 | 39: 2 | Fisher's | 1.000 | |
| Handedness (right: left: ambidextrous) | 37: 5: 1 | 34: 6: 1 | Fisher's | 0.875 | |
| Age (years) | 41.7 (±10.6) | 40.5 (±7.6) | 0.60 | 0.553 | |
| Body mass index | 24.8 (±3.1) | 23.4 (±4.1) | 1.75 | 0.084 | |
| Alcohol consumption (AUDIT score) | 3.9 (±1.9) | 4.0 (±4.8) | 1.24 | 0.222 | |
| Selected markers related to iron status | |||||
| Dietary iron (mg) | 11.6 (±3.7) | 13.4 (±6.2) | −1.66 | 0.100 | |
| Serum iron (μmol l−1) | 17.9 (±5.9) | 12.8 (±5.5) | 4.03 | <0.001 | |
| Serum ferritin (μg l−1) | 65.0 (±46.1) | 103.2 (±75.2) | −2.80 | 0.008 | |
| Serum transferrin (g l−1) | 2.8 (±0.4) | 2.6 (±0.4) | 1.13 | 0.332 | |
| Transferrin saturation (%) | 29.1 (±9.6) | 21.9 (±10.3) | 3.32 | 0.001 | |
| Serum hepcidin-25 (nm) | 3.4 (±3.8) | 3.7 (±3.0) | 710.5 | 0.125 | |
| Selected inflammatory marker | |||||
| C-reactive protein (mg l−1) | 2.5 (±2.6) | 9.2 (±9.8) | 436.5 | <0.001 | |
| Selected haematology markers | |||||
| Haemoglobin (g l−1) | 143.9 (±7.5) | 136.9 (±12.1) | 3.15 | 0.002 | |
| Haematocrit (l l−1) | 0.4 (±0.02) | 0.4 (±0.04) | 2.43 | 0.018 | |
| Red blood cells (1012 per l) | 4.8 (±0.3) | 4.6 (±0.4) | −3.37 | 0.001 | |
| White blood cells (109 per l) | 5.9 (±1.3) | 7.4 (±2.6) | 1.73 | 0.088 | |
| Eosinophils (%) | 1.8 (±1.1) | 3.3 (±1.7) | −4.73 | <0.001 | |
| Lymphocytes (%) | 28.3 (±6.4) | 33.7 (±10.2) | −2.92 | 0.005 | |
| Monocytes (%) | 7.50 (±1.8) | 8.6 (±2.5) | −2.31 | 0.024 | |
| Neutrophils (%) | 61.8 (±7.0) | 53.7 (±11.7) | 3.82 | <0.001 | |
| Basophils (%) | 0.6 (±0.3) | 0.7 (±0.4) | −0.90 | 0.369 | |
| Mean cell volume (Fl) | 89.4 (±4.6) | 88.8 (±6.4) | 0.52 | 0.602 | |
| Mean cell haemoglobin (Pg) | 30.3 (±1.7) | 29.7 (±2.4) | 1.18 | 0.242 | |
| Mean corpuscular haemoglobin concentration | 338.5 (±6.9) | 334.63 (±8.3) | 2.27 | 0.026 | |
| Other biomarkers | |||||
| Creatinine (μmol l−1) | 79.9 (±14.4) | 79.7 (±16.1) | 0.04 | 0.970 | |
| Total bilirubin (μmol l−1) | 14.2 (±9.8) | 6.5 (±3.3) | 302.5 | <0.001 | |
| Conjugated bilirubin (μmol l−1) | 3.9 (±2.5) | 2.5 (±1.3) | 555.5 | 0.003 | |
Abbreviations: Std., standard deviation.
Means and standard deviations appear in parentheses.