Table 1. Top significantly modulated genes by SLEs exposure.
| Gene Assignment | Gene symbol | Fold change (SLE vs. No SLE) | |
|---|---|---|---|
| 1 | CD38 molecule | CD38 | −1.4 |
| 2 | Ring finger protein 182 | RNF182 | −1.4 |
| 3 | SLAM family member 7 | SLAMF7 | −1.4 |
| 4 | Perforin-1 (pore forming protein) | PRF1 | −1.4 |
| 5 | SH2 domain containing 1B | SH2D1B | −1.4 |
| 6 | Immunoglobulin heavy variable 3–33 | IGHV3-33 | −1.3 |
| 7 | Immunoglobulin lambda joining 3 | IGLJ3 | −1.3 |
| 8 | Immunoglobulin heavy variable 3–38 | IGHV3-38 | −1.3 |
| 9 | Fc receptor-like 5 | FCRL5 | −1.3 |
| 10 | Histone cluster 1, H3i | HIST1H3I | −1.3 |
| 11 | G-protein-coupled receptor 56 | GPR56 | −1.3 |
| 12 | Transforming growth factor, beta receptor III | TGFBR3 | −1.3 |
| 13 | S100 calcium binding protein A9 | S100A9 | 1.2 |
| 14 | Cystatin A (stefin A) | CSTA | 1.2 |
| 15 | Carboxymethylenebutenolidase homolog | CMBL | 1.2 |
| 16 | Ribosomal protein S26 | RPS26 | 1.2 |
| 17 | RNA, 5S ribosomal 399 | RN5S399 | 1.3 |
| 18 | Ribosomal protein L7 | RPL7 | 1.3 |
| 19 | Interleukin 8 | IL8 | 1.3 |
| 20 | Tubulin, beta 4B class Ivb | TUBB4B | 1.3 |
| 21 | Lymphocyte antigen 96 | LY96 | 1.3 |
| 22 | Ribosomal protein L21 | RPL21 | 1.3 |
| 23 | S100 calcium binding protein A8 | S100A8 | 1.4 |
| 24 | KIAA1324 | KIAA1324 | 1.6 |
Abbreviation: SLE, stressful life event.
Selection of the 24 genes with the lowest or highest values of fold change (all q-value<0.05), 12 downregulated and 12 upregulated.