Table 4. Rates of HIV-related illnesses in four CD4 cell count strata during the first 5 years of first line antiretroviral therapy.
| Type of HIV-related illness | CD4 < 200 cells/μl Rate per 100PYAR (95% CI) | CD4 200–350 cells/μl Rate per 100PYAR (95% CI) | CD4 351–500 cells/μl Rate per 100PYAR (95% CI) | CD4 >500 cells/μl Rate per 100PYAR (95% CI) |
|---|---|---|---|---|
| Pulmonary TB | 15.98 (15.47–16.51) | 1.45 (1.29–1.63) | 1.05 (0.87–1.27) | 0.98 (0.87–1.10) |
| Oral candidiasis | 12.5 (12.03–12.94) | 0.75 (0.64–0.89) | 0.61 (0.47–0.78) | 0.60 (0.54–0.72) |
| Herpes Zoster | 6.30 (5.99–6.64) | 0.99 (0.86–1.14) | 0.84 (0.68–1.04) | 0.60 (0.52–0.71) |
| Chronic diarrhoea | 5.48 (5.18–5.78) | 1.22 (1.07–1.39) | 1.08 (0.89–1.31) | 0.84 (0.71–0.91) |
| Esophageal candidiasis | 1.98 (1.81–2.17) | 0.20 (0.15–0.28) | 0.14 (0.08–0.23) | 0.15 (0.13–0.23) |
| Kaposi Sarcoma | 1.82 (1.66–2.01) | 0.30 (0.23–0.39) | 0.18 (0.11–0.28) | 0.13 (0.09–0.18) |
| Pneumocystis carinii pneumonia | 1.86 (1.69–2.04) | 0.30 (0.23–0.39) | 0.14 (0.08–0.23) | – |
| Cryptococcal meningitis | 1.06 (0.93–1.20) | 0.38 (0.30–0.47) | 0.28 (0.19–0.40) | – |
| Herpes Simplex Virus | 1.43 (1.28–1.59) | 0.32 (0.25–0.42) | 0.18 (0.11–0.28) | 0.18 (0.13–0.24) |
| Extrapulmonary TB | 1.12 (1.00–1.27) | 0.30 (0.23–0.39) | 0.28 (0.19–0.40) | – |
| Toxoplasmosis | 0.51 (0.42–0.61) | 0.09 (0.06–0.15) | 0.04 (0.02–0.12) | – |
| Pruritic purpura eruptions | 3.33 (3.13–3.54) | 1.61 (1.44–1.27) | 1.11 (0.92–1.34) | 0.97 (0.86–1.09) |
| Recurrent URTI | 2.56 (2.39–2.74) | 1.11 (0.97–1.27) | 0.82 (0.66–1.01) | 1.00 (0.89–1.13) |
TB, tuberculosis, URTI, Upper respiratory tract infection.