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. 2017 Jun;45(6):635–645. doi: 10.1124/dmd.117.075317

Fig. 8.

Fig. 8.

Differences in 17,20-lyase inhibition (solid lines) and progesterone hydroxylase inhibition (dashed lines) demonstrate less selectivity for 17,20-lyase inhibition by (A) (S)-orteronel compared with (B) (R)-orteronel.