Table 2. Association of SCAP polymorphisms with blood pressure level in Chinese children.
Phenotypes | rs12487736 | rs12490383 | ||||
---|---|---|---|---|---|---|
(0 = GG, 1 = GA/AA) | (0 = CC, 1 = CT/TT) | |||||
β | 95%CI | P-value* | β | 95%CI | P-value* | |
SBP(mmHg) | 1.66 | 0.55,2.78 | 0.003 | 1.71 | 0.54,2.88 | 0.004 |
DBP(mmHg) | 1.35 | 0.18,2.53 | 0.024 | 0.45 | -0.79,1.68 | 0.481 |
Abbreviations: SBP/ DBP: systolic/diastolic blood pressure. β with 95% confidence interval (CI) and P-value was estimated with linear regression analysis under dominant model with age, age-squared, sex, study population and BMI adjusted.
* The associations remained significant after further adjustment for lipid parameters (triglycerides /total cholesterol/low-density lipoprotein cholesterol / high-density lipoprotein cholesterol) in the multivariable models.