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. 2017 May 19;12(5):e0177973. doi: 10.1371/journal.pone.0177973

Table 2. Association of SCAP polymorphisms with blood pressure level in Chinese children.

Phenotypes rs12487736 rs12490383
(0 = GG, 1 = GA/AA) (0 = CC, 1 = CT/TT)
β 95%CI P-value* β 95%CI P-value*
SBP(mmHg) 1.66 0.55,2.78 0.003 1.71 0.54,2.88 0.004
DBP(mmHg) 1.35 0.18,2.53 0.024 0.45 -0.79,1.68 0.481

Abbreviations: SBP/ DBP: systolic/diastolic blood pressure. β with 95% confidence interval (CI) and P-value was estimated with linear regression analysis under dominant model with age, age-squared, sex, study population and BMI adjusted.

* The associations remained significant after further adjustment for lipid parameters (triglycerides /total cholesterol/low-density lipoprotein cholesterol / high-density lipoprotein cholesterol) in the multivariable models.