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. 2017 May 19;12(5):e0177973. doi: 10.1371/journal.pone.0177973

Table 5. Association between SCAP polymorphisms and systolic high blood pressure risk stratified by BMI categories in Chinese children.

SNP BMI categories Genotype Frequency (%) OR(95%CI) P-value
Non-SHBP SHBP
rs12487736
(0 = GG, 1 = GA/AA)
Normal-weight group GG 148(94.27) 9(5.73) 0.86(0.37,1.91) 0.678
GA/AA 424(95.5) 20(4.5)
Overweight/obese group GG 285(71.79) 112(28.21) 1.36(1.02,1.82) 0.037
GA/AA 679(67.29) 330(32.71)
rs12490383
(0 = CC, 1 = CT/TT)
Normal-weight group CC 124(93.94) 8(6.06) 0.76(0.32,1.78) 0.527
CT/TT 450(95.54) 21(4.46)
Overweight/obese group CC 246(72.78) 92(27.22) 1.50(1.10,2.05) 0.01
CT/TT 719(67.13) 352(32.87)

Abbreviations: SHBP: systolic high blood pressure. Odds ratio(OR) with 95% confidence interval (CI) and P-value was estimated with logistic regression analysis under dominant model with age, age-squared, sex, study population and BMI adjusted.