Fig 4. KEGG pathway enrichment analysis of differentially expressed genes between S28 and S6.

Enrichment factor is calculated as followed:

$$\mathrm{Enrichment}\mathrm{factor}=\frac{\mathrm{Gene}\mathrm{hits}/{\mathrm{Gene}}_{\mathrm{pathway}}}{{\mathrm{Hits}}_{\mathrm{total}}/{\mathrm{Gene}}_{\mathrm{total}}}$$

Gene hits is the number of hits in the selected pathway; Gene_pathway is the number of genes in the selected pathway of KEGG background; Hits_total represents the number of total hits in all pathways; Gene _total is the number of total genes in all pathways of KEGG background.