Fig 9. Acute PDE4B inhibition did not rescue spatial working memory deficits at 1 month post-TBI.

(A) Path length from location and match trials. (B) Path length analysis of match trial. Both vehicle and A33-treated TBI animals had significantly impaired working memory, as measured by an increase in path length in the match trial as compared to sham animals. Mean ± SEM, n = 12-14/group, *p<0.05, **p<0.01 vs. Sham, one-way ANOVA with post-hoc Student-Newman-Keuls.