Figure 4. Trafficking of cis-SNARE complexes during cytokinesis (model).
Two different types of cytokinetic cis-SNARE complexes are assembled on the ER, recruited into COPII vesicles and passed on to the Golgi stack/TGN. At the TGN, they are incorporated into AP1/CCV vesicles for delivery to the division plane. Following their disassembly by NSF ATPase, monomeric Qa-SNARE KNOLLE is assisted by SM protein KEULE in the formation of trans-SNARE complexes mediating fusion of adjacent vesicles during cell-plate formation and expansion (Park et al., 2012).