Table 1.
Model parameters. A full discussion of parameter selection is available in supplemental information.
Parameter | Definition | Initial value | |
---|---|---|---|
u | Strategy (phenotype) | 0 | |
x | Population density | 100 | |
Kmax | Carrying capacity | 100 | |
r | Growth rate | 0.1 | |
m | Drug dosage | 0.1 | |
|
Cost of resistance | 1 | |
b | Strategy effectiveness | 5 | |
k | Naïve drug efficacy | 0.1 | |
α | Aggregation parameter | [−0.5, 0, 1, 1.5] | |
β | Aggregation parameter | [−0.5, 0, 6] | |
N | Neighborhood size | [1, 5, x/10 + 1, 10, x] |