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. Author manuscript; available in PMC: 2017 May 20.
Published in final edited form as: JPEN J Parenter Enteral Nutr. 2016 Jul 11;41(2):181–187. doi: 10.1177/0148607116640275

Figure 3. PFO66 and PFO90 result in histologic abnormalities in liver, spleen, and lungs, while NFO preserves normal organ architecture.

Figure 3

Saline, OM, SO, and NFO groups demonstrated histologically normal livers (top row), spleens (middle row), and lungs (bottom row) after 19 days of treatment. PFO66 and PFO90 groups developed hepatic and splenic lipid-laden macrophages without evidence of inflammation or necrosis; as well as pulmonary fat deposits. All panels are stained with hematoxylin and eosin. Magnification is 400X for all groups. For PFO66 and PFO90 groups, a portion of hepatic and pulmonary slides further magnified to emphasize lipid-laden macrophages and pulmonary fat.