Table 2.
Clinical characteristics at baseline and during intensive care unit hospitalization.
| Entire population | Survival outcome at 1 year (N = 108) | P | |||||
|---|---|---|---|---|---|---|---|
| Deceased | Survived | ||||||
| N | 112 | 83 | 25 | ||||
| Age (years) | 69.0 ± 14.7 | 69.9 ± 14.5 | 66.7 ± 15.9 | 0.341 | |||
| Sex | 0.464 | ||||||
| Male | 65 | (58.0) | 50 | (60.2) | 13 | (52.0) | |
| Female | 47 | (42.0) | 33 | (39.8) | 12 | (48.0) | |
| Cancer status* | 0.005 | ||||||
| Controlled non-hematologic cancer | 52 | (46.4) | 32 | (38.6) | 17 | (68.0) | |
| Uncontrolled non-hematologic cancer | 37 | (33.0) | 35 | (42.2) | 2 | (8.0) | |
| Without non-hematologic cancer | 23 | (20.5) | 16 | (19.3) | 6 | (24.0) | |
| Co-morbidities | |||||||
| Congestive heart failure | 13 | (11.6) | 9 | (10.8) | 4 | (16.0) | 0.493 |
| Diabetes mellitus | 35 | (31.3) | 29 | (34.9) | 6 | (24.0) | 0.306 |
| Chronic lung disease | 19 | (17.0) | 12 | (14.5) | 7 | (28.0) | 0.139 |
| Cirrhosis | 6 | (5.4) | 6 | (7.2) | 0 | 0 | 0.333 |
| Neurologic disease | 23 | (20.5) | 18 | (21.7) | 4 | (16.0) | 0.536 |
| Chronic kidney disease | 18 | (16.1) | 13 | (15.7) | 5 | (20.0) | 0.76 |
| ICU admission | |||||||
| APACHE II | 27.0 ± 7.9 | 26.8 ± 7.5 | 28.0 ± 9.3 | 0.477 | |||
| SOFA | 7.5 ± 3.5 | 7.6 ± 3.5 | 7.0 ± 3.5 | 0.473 | |||
| Severe sepsis/septic shock | 57 | (50.9) | 45 | (54.2) | 9 | (36.0) | 0.11 |
| Pneumonia | 79 | (83.2) | 59 | (83.1) | 17 | (81.0) | 0.755 |
| ARDS | 22 | (19.6) | 19 | (22.9) | 3 | (12.0) | 0.236 |
| Acute kidney injury† | 30 | (28.6) | 22 | (28.6) | 8 | (33.3) | 0.656 |
| ICU stay | |||||||
| Infection‡ | 60 | (53.6) | 44 | (54.2) | 12 | (48.0) | 0.585 |
| Severe sepsis/septic shock‡ | 21 | (18.8) | 16 | (19.3) | 4 | (16.0) | >0.999 |
| Length of stay (days) | 27.7 ± 14.2 | 29.5 ± 15.5 | 23.0 ± 8.0 | 0.046 | |||
Data are presented as the mean ± standard deviation or number (%). APACHE II, Acute Physiology and Chronic Health Evaluation score; ARDS, acute respiratory distress syndrome; ICU, intensive care unit; SOFA, Sequential Organ Failure Assessment score. *Disease conditions classified as cure, complete remission, partial remission, or stable disease were considered under control, while those classified as progressive or newly-diagnosed diseases were considered uncontrolled. In patients with non-hematologic malignancies from two different origins, the disease status was defined as uncontrolled if either one was uncontrolled. †In patients without end-stage renal disease before admission. ‡Hospital-acquired infection and hospital-acquired severe sepsis/septic shock.