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. 2017 May 19;7:2141. doi: 10.1038/s41598-017-01490-0

Figure 1.

Figure 1

The E. coli biotin biosynthesis pathway and genetic organizations of the E. coli and P. aeruginosa biotin synthesis genes. (a) Scheme of the biotin synthesis pathway. (b) The biotin synthesis gene organizations of E. coli and P. aeruginosa. Note that in E. coli, the five bioABFCD genes are located within the biotin synthesis (bio) operon at min 17 of the chromosome map whereas the bioH gene is well removed from the bio operon at min 74 of the genetic map (note the broken lines).