Analysis of chymotrypsin-like activities in brain homogenates from BA9, BA40, and BA24 of DLB, PDD, AD, and controls. Scatter plots are shown of chymotrypsin-like activity measurement in BA9, BA40, and BA24 homogenates from DLB, PDD, AD, and normal control samples using the fluorogenic substrate assay. Activities are expressed as fluorescence units (FU)/mg protein/hour. BA9; the activities’ values for the control group were significantly higher than the PDD (p = 0.004, n = 12), DLB (p = 0.013, n = 11) and AD (p = 0.001, n = 6) groups. The ANOVA values for chymotrypsin-like activity measurement in BA9 are: F = 7.897, d.f. = 3 and 34, p = 0.001) BA40; the activities’ values for the control group (n = 13) were significantly higher than the PDD (p = 0.001, n = 10), DLB (p = 0.001, n = 9), and AD (p = 0.001, n = 12) groups. The ANOVA for chymotrypsin-like activity measurement in BA40 (one-way ANOVA, F = 30.033, d.f. = 3 and 40, p = 0.001; Bonferroni post hoc test) BA24; there was a significant difference between the PDD (p = 0.015, n = 9) and AD (p = 0.044, n = 9) groups compared with the control (n = 13) (one-way ANOVA, F = 4.664, d.f. = 3 and 39, p = 0.007; Bonferroni post hoc test). (**p < 0.01).