Table 2.

Receiver-operating characteristic (ROC) and area under the curve (AUC) analysis of amyloid-β (Aβ), thioflavin-S (Th-S), and butyrylcholinesterase (BChE) associated pathology in the orbitofrontal cortex in predicting confirmed neuropathological diagnosis (gold standard)

Plaque Burden	AUC	% Area with	Sensitivity (%)	Specificity (%)
		pathology cut-off
Aβ	0.98±0.02	10.5	100.0	85.7
Th-S	0.99±0.01	0.5	100.0	92.9
BChE	1.00±0.00	5.8	100.0	100.0