Table 1.
Patients’ characteristics and clinical data
| Characteristic | Group G (n = 40) | Group R (n = 44) | Group GR (n = 40) | P value (overall) |
|---|---|---|---|---|
| Age (year) | 44.5 ± 11.1 | 44.2 ± 9.7 | 43.2 ± 9.2 | 0.831 |
| Height (cm) | 157.3 ± 5.4 | 158.3 ± 6.7 | 157.8 ± 4.9 | 0.753 |
| Weight (kg) | 60.5 ± 9.7 | 59.7 ± 11.3 | 61.9 ± 10.1 | 0.620 |
| PONV history | 4 (10.0) | 3 (6.8) | 2 (5.0) | 0.683 |
| Motion sickness history | 3 (7.5) | 8 (18.2) | 6 (15.0) | 0.349 |
| Nonsmoking status | 37 (92.5) | 39 (88.6) | 36 (90.0) | 0.833 |
| Apfel’s risk score for PONV | 0.465 | |||
| 3 | 5 (12.5) | 10 (22.7) | 8 (20.0) | |
| 4 | 35 (87.5) | 34 (77.3) | 32 (80.0) | |
| Type of laparoscopic surgery | 0.414 | |||
| Total hysterectomya | 13 (32.5) | 21 (47.7) | 21 (52.5) | |
| Ovarian cystectomy | 17 (42.5) | 10 (22.7) | 9 (22.5) | |
| Myomectomy | 6 (15.0) | 7 (15.9) | 5 (12.5) | |
| Salpingo-oophorectomy | 4 (10.0) | 6 (13.6) | 5 (12.5) | |
| Duration of surgery (min) | 102.0 ± 58.8 | 101.1 ± 53.1 | 101.3 ± 44.0 | 0.997 |
| Duration of anesthesia (min) | 146.1 ± 61.0 | 141.9 ± 58.1 | 136.1 ± 46.1 | 0.721 |
| ASA class I/II | 24/16 | 25/19 | 21/19 | 0.794 |
Data presented as mean ± SD or n (%) of patients
Data were analyzed using ANOVA (continuous variables) or χ 2 test (incidence variables)
Group G, patients received oral gabapentin 300 mg 1 h before induction of anesthesia; Group R, patients received intravenous ramosetron 0.3 mg at the end of surgery; Group GR, patients received oral gabapentin 300 mg 1 h before induction of anesthesia and intravenous ramosetron 0.3 mg at the end of surgery; PONV postoperative nausea and vomiting; Apfel’s risk score consists of four predictors: nonsmoking, female, history of motion sickness and/or PONV, postoperative opioid; ASA American Society of Anesthesiologists’ physical status
a In some patients, salpingo-oophorectomy was perforemed together