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. 2017 May 19;17:56. doi: 10.1186/s12935-017-0427-5

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — a–d Invasive carcinomas of the breast (hormone receptor+) representative of the majority of cases in Fig. 2a (orange box). While there are a number of CD34+ stromal vessels in each case (right panels), only an occasional tumor stromal vessel shows immunoreactivity for VEGFR2 (left panels). a Invasive lobular carcinoma without obvious VEGFR2+ vessels in tumor stroma. b Invasive ductal carcinoma. c Mucinous carcinoma with a mixture of VEGFR2+ (black arrow) and VEGFR2− vessels in the tumor stroma. d Invasive lobular carcinoma with an occasional VEGFR2+ vessel in the tumor stroma. Original magnification ×200