Fig. 4.

a–d Invasive carcinomas of the breast (HER2+) representative of the significant proportion of cases in Fig. 2b (orange box). Overall, these cases show significantly higher numbers of VEGFR2+ tumor vessel counts and crisp brown staining for VEGFR2 protein in majority of the tumor stromal vessels (left panels, black arrows), despite variable numbers of CD34+ tumor stromal vascular counts (right panels). a Invasive ductal carcinoma. b Invasive breast carcinoma with lobular features. c Invasive ductal carcinoma. d Invasive lobular carcinoma. Original magnification ×200