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. 2017 Mar 8;8(17):27715–27724. doi: 10.18632/oncotarget.16016

Figure 1. RIP3 deficiency promotes survival in mice infected with H7N9 virus despite virus control.

Figure 1

A. and B. (A) Survival and (B) body weight changes of H7N9 virus-infected WT (n = 16) and RIP3−/− (n = 24) mice compared to PBS-inoculated WT and RIP3−/− mice (n = 12) (**p < 0.01). c. H7N9 virus HA gene of lung tissues was measured by qPCR at 2, 3, 5 and 7 days p.i. D. H7N9 virus HA protein of lung tissues was detected by immunostaining. Scale bar indicates 100μm. Data collected from three independent experiments (n = 6 mice per genotype per time point) was shown as mean±SEM. Each line in (B) represents an individual mouse.