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. 2017 Feb 24;8(17):27839–27853. doi: 10.18632/oncotarget.15711

Figure 2. DLEU1 downregulates cell proliferation and upregulates caspase-dependent apoptosis.

Figure 2

(A, C) Comparison of DLEU1-KD vs WT (A) and GFP-DLEU1 vs GFP (C) cell proliferation. (B, D) Caspase 3/7 activity in DLEU1-KD vs WT cells (B) and GFP-DLEU1 vs GFP cells (D). (E–H) mRNA (E, F) and protein (G, H) expression of anti-apoptotic and pro-apoptotic genes in the Bcl-2 family in DLEU1-KD vs WT (E, G) and GFP-DLEU1 vs GFP (F, H) cells. Data are represented as the mean ± SD of triplicates (paired t test). *p < 0.05; **p < 0.01.