Skip to main content
. 2017 Mar 2;8(17):27953–27965. doi: 10.18632/oncotarget.15853

Figure 6. Model of SNS-314 on apoptosis of HCC cells.

Figure 6

The inhibition of Aurora A and B kinases induced by SNS314 resulted in the reduction of YAP, furthermore, resulted in P21 accmulation which promoted the apoptosis of HCC cells. Also, knockdown of P21 could enhance YAP protein level.