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. 2017 Mar 6;8(17):28116–28124. doi: 10.18632/oncotarget.15922

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Copyright: © 2017 Oei et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Relative tumour volume demonstrated that PARP1-i enhanced the effectiveness of cDDP-based thermochemotherapy and reduced the in vivo tumour outgrowth. Arrows present the time of treatment. (B) Time needed to achieve ten times the start volume (T10 × SV). Animals treated with the triple modality showed a delay in reaching T10 × SV compared to thermochemotherapy or any single treatment. All animal experiments included at least five rats per group.