Table 4. IL-1A and IL-1B haplotype frequencies and the association with the risk of ankylosing spondylitis in case and control patients (adjusted sex and age).

Gene	SNPs	Haplotype	Freq (case)	Freq(control)	OR(95% CI)	P-value*
IL-1A	rs3783550/rs3783546/rs2856838	GGG	0.662	0.680	1(referent)	—
		TCA	0.252	0.237	0.72(0.44–1.18)	0.19
		TCG	0.086	0.083	0.36(0.16–0.81)	0.014*
IL-1B	rs1143630/rs1143627/rs16944/rs1143623	CAGC	0.530	0.517	1(referent)	—
		GGAG	0.223	0.255	1.08(0.68–1.73)	0.74
		TGAG	0.178	0.151	0.89(0.52–1.52)	0.67
		GGAC	0.066	0.070	0.68(0.30–1.56)	0.37

*p value ≤ 0.05 indicates statistical signifcance.