Figure 5. Selective killing of tumor endothelial cells by sera from ValloVax immunized mice.

Sera was collected from C57/BL6 mice that were either: unimmunized; immunized with HEL; or immunized with ValloVax. Sera was incubated with either healthy bone marrow derived endothelium A. or bone marrow derived tumor-like endothelium B. Viability was represented as percentage of absorbance with untreated cells. Six mice per group were utilized and in vitro culture was representative of triplicate experiments performed at least 3 times (*p < 0.01 as compared to control).