Table 4. Genotypes of the six SNPs and their associations with risk of SCZ.
| SNP-ID | Genotype | Case(N) | Control(N) | Without adjustment | With adjustment | ||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | ||||
| rs12573128 | GG | 257 | 295 | 1.00 | - | 1.00 | - | ||
| AG | 205 | 185 | 1.27 | 0.98-1.65 | 0.070 | 1.34 | 0.98-1.83 | 0.067 | |
| AA | 36 | 20 | 2.07 | 1.17-3.66 | 0.013 | 2.97 | 1.49-5.92 | 0.002 | |
| rs7081062 | AA | 275 | 302 | 1.00 | - | 1.00 | - | ||
| GA | 195 | 172 | 1.25 | 0.96-1.62 | 0.101 | 1.30 | 0.95-1.7 | 0.101 | |
| GG | 28 | 26 | 1.18 | 0.68-2.07 | 0.556 | 1.38 | 0.70-2.73 | 0.358 | |
| rs4918789 | TT | 448 | 462 | 1.00 | - | 1.00 | - | ||
| GT | 50 | 37 | 1.39 | 0.89-2.17 | 0.143 | 1.43 | 0.86-2.39 | 0.169 | |
| GG | 0 | 1 | 0.00 | - | 0.999 | 0.00 | - | 0.999 | |
| rs3750804 | CC | 293 | 285 | 1.00 | - | 1.00 | - | ||
| TC | 181 | 189 | 0.93 | 0.72-1.21 | 0.594 | 0.85 | 0.62-1.17 | 0.322 | |
| TT | 25 | 26 | 0.94 | 0.53-1.66 | 0.819 | 1.08 | 0.55-2.12 | 0.815 | |
| rs6585205 | GG | 142 | 156 | 1.00 | - | 1.00 | - | ||
| TG | 255 | 247 | 1.13 | 0.85-1.51 | 0.390 | 1.02 | 0.72-1.44 | 0.903 | |
| TT | 101 | 96 | 1.16 | 0.81-1.66 | 0.431 | 1.30 | 0.85-1.99 | 0.234 | |
| rs290489 | GG | 222 | 209 | 1.00 | - | 1.00 | - | ||
| AG | 211 | 234 | 0.85 | 0.65-1.11 | 0.226 | 0.85 | 0.62-1.16 | 0.302 | |
| AA | 65 | 57 | 1.07 | 0.72-1.61 | 0.730 | 0.95 | 0.58-1.55 | 0.832 | |
Abbreviations: SNP: Single nucleotide polymorphism; OR: Odds ratio; 95% CI: 95% Confidence interval.
P values were calculated using the Wald test.
P < 0.05 indicates statistical significance.