Table 4. Diagnostic performances of noninvasive models for liver fibrosis and cirrhosis.
| Significant fibrosis | Severe fibrosis | Cirrhosis | ||||
|---|---|---|---|---|---|---|
| AUROC | (95% CI) | AUROC | (95% CI) | AUROC | (95% CI) | |
| GPR | 0.86 | (0.79–0.91) | 0. 89 | (0.82–0.94) | 0.92 | (0.87–0.96) |
| APRI | 0.75 | (0.66–0.82) | 0.77 | (0.68–0.84) | 0.86 | (0.79–0.92) |
| FIB-4 | 0.66 | (0.57–0.74) | 0.72 | (0.70–0.80) | 0.73 | (0.65–0.80) |
| Comparison of AUROC | ||||||
| GPR and APRI | p = 0.001 | p = 0.002 | p = 0.104 | |||
| GPR and FIB-4 | p < 0.001 | p = 0.001 | p < 0.001 | |||
| APRI and FIB-4 | p = 0.048 | p = 0.46 | p = 0.039 | |||
GPR, gamma-glutamyl transpeptidase to platelet ratio index; APRI, aspartate transaminase to platelet ratio index; FIB-4, fibrosis index based on the 4 factors; AUROC, the area under the receiver operating characteristic curve; CI, confidence interval.