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. 2017 Feb 23;8(17):28683–28695. doi: 10.18632/oncotarget.15640

Figure 2. The effects of miR-146b-5p on proliferation, apoptosis, migration, and invasion of HCC cells.

Figure 2

A. Expression of miR-146b-5p in the human immortal liver cell line (LO2) and four HCC cell lines (MHCC97-H, SMMC-7721, Hep3B and HepG2). ***P<0.001. B. Alteration of miR-146b-5p levels in HCC cells according their basal levels. miR-146b-5p expression levels were determined by qRT-PCR. ***P<0.001. C-G. Alteration of miR-146b-5p expression levels markedly influenced cell viability (C), colony numbers (D), apoptotic cell percentages (E), caspase 3/7 enzyme activity (F), migration and invasion (G) in MHCC97-H and Hep3B cells. *P<0.01. All experiments were performed at least in triplicate and the data in A-G are presented as the (mean ± SD).