. 2017 Feb 23;8(17):28683–28695. doi: 10.18632/oncotarget.15640

Table 1. Clinical correlation of miR-146b-5p expression in HCC (N=60).

Clinical Characteristics		No. of patients (N=60)	No. of patients (N=60)		χ²	P
Clinical Characteristics		No. of patients (N=60)	146b-5p^Highn=25	146b-5p^Low n=35	χ²	P
Gender	Male	39	15	24	0.471	0.493
Gender	Female	21	10	11	0.471	0.493
Age (year)	<50	29	11	18	0.322	0.570
Age (year)	≥50	31	14	17	0.322	0.570
Tumor size (cm)	<5	24	14	10	4.571	0.033*
Tumor size (cm)	≥5	36	11	25	4.571	0.033*
Liver cirrhosis	Absent	13	7	6	1.013	0.314
Liver cirrhosis	Present	47	18	29	1.013	0.314
Serum AFP level (ng/mL)	<400	20	11	9	2.194	0.139
Serum AFP level (ng/mL)	≥400	40	14	26	2.194	0.139
Venous infiltration	Absent	42	21	21	4.000	0.046*
Venous infiltration	Present	18	4	14	4.000	0.046*
Edmondson-Steiner grading	I+II	35	11	24	3.623	0.057
Edmondson-Steiner grading	III+IV	25	14	11	3.623	0.057
TNM stage	I+II	39	20	19	4.239	0.040*
TNM stage	III+IV	21	5	16	4.239	0.040*

*P<0.05.

Abbreviations: AFP, alpha-fetoprotein; TNM, tumor-node-metastasis.