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. 2017 Feb 23;8(17):28696–28710. doi: 10.18632/oncotarget.15645

Figure 3. Effects of pharmaceutical inhibition of CDK9 on cell proliferation, apoptosis and cell cycle.

Figure 3

Cell proliferation was measured after the treatment of CAN508 for 72 hours (A, left panel) or Flavopiridol for 48 hours (A, right panel) by MTS assay using Cell Titer Aqueous One Solution Cell Proliferation Assay kit. The apoptosis (B) and cell cycle phases (C) of esophageal adenocarcinoma cells were determined by flow cytometry. Values are shown as means ± SE of 3 independent experiments. *represents p-value <0.05 compared to untreated controls.