Table 1. CDK9 staining in matched samples of Barrett's Esophagus and esophageal adenocarcinoma (n=10).
Percentage of cells with CDK9 staining intensity | p value | ||||
---|---|---|---|---|---|
0, mean (range) | 1, mean (range) | 2, mean (range) | 3, mean (range) | ||
BE surface | 48 (12-90) | 17 (0-44) | 25 (6-43) | 10 (0-48) | <0.01* |
BE upper half | 21 (1-57) | 16 (0-35) | 36 (22-48) | 27 (10-75) | <0.01** |
BE lower half | 3 (0-7) | 7 (0-23) | 19 (6-34) | 73 (31-94) | |
BE total | 23 (4-51) | 15 (1-45) | 25 (14-34) | 37 (16-71) | <0.01*** |
Invasive adenocarcinoma | 0 | 0 | 10 (0-15) | 90 (80-100) |
*p value for for intensity 0, 2, and 3 compared between surface and upper 1/2. p value for staining intensity 1 between surface and upper half of cryptis 0.39
** p value for for intensity 0,1, 2, and 3 compared between upper 1/2 and lower 1/2 of the crypt of BE
*** p value for intensity o,1,2,3 between invasive adenocarcinoma and total BE.