Figure 7. Nrf2, NQO1 and MRP1 proteins level in IDH1 R132H overexpressing U87 cells and U251 cells.

Base level of NQO1 and MRP1 in U87 and U251 cells (A). After 400 μM TMZ treatment for 72 h, the expression level of NQO1 and Nrf2 in U87 (B) and U251 cells was measured (C). Western blotting experiments were performed in triplicate and representative images are shown. Quantification of protein expression is shown at the side or below the images. ***P < 0.001 compared with MT.