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. 2017 Mar 7;8(17):29013–29027. doi: 10.18632/oncotarget.15994

Table 2. Synergistic effects of SsaI and EGFR inhibitor.

SsaI (μM) AG1478 (μM) CI*
100 2.5 1.17
100 5 0.92
100 25 0.84
25 25 0.78
25 50 0.57

* Combination index (CI) is a quantitative measure of the degree of interaction between different drugs. If CI =1, it denotes additivity; if CI > 1, it denotes antagonism; and if CI < 1, it denotes synergism.