Table 4. Cox proportional hazard analysis for time-to-CCRT responses (including complete and partial response) in relation to clinical parameters.

Clinical parameters	Univariate analysis			Multivariate analysis
	HR	95% CI	P	HR	95%CI	P
Age, per year increase	1.008	0.980 – 1.036	0.595
Gender, Male vs. Female	0.203	0.047 – 0.886	0.034	0.242	0.055 – 1.064	0.060
Location of tumor
Upper vs. other	0.939	0.453 – 1.950	0.867
Middle vs. other	1.130	0.604 – 2.116	0.703
Lower vs. other	1.539	0.726 – 3.262	0.261
Histology, Poorly differentiated = 1	0.927	0.479 – 1.794	0.822
Tumor stage, per stage increase	1.222	0.788 – 1.896	0.371
Metastasis stage, per stage increase	1.080	0.793 – 1.472	0.623
ECOG Stage, greater than one = 1	0.476	0.166 – 1.367	0.168
Tumor length, per cm increase	1.007	1.000 – 1.015	0.065
Albumin, per g/dL increase	1.605	0.895 – 2.877	0.112
Alanine transaminase, per U/L increase	1.004	0.983 – 1.025	0.721
Creatinine, per mg/dL increase	0.716	0.264 – 1.943	0.511
Bilirubin, per mg/dL increase	0.902	0.424 – 1.920	0.790
Leukocytes, per × 109/L increase	1.084	1.016 – 1.156	0.014	1.087	1.017 – 1.161	0.014
Neutrophil percentage, per % increase	5.022	0.439 – 57.443	0.194
Hemoglobin, per g/dL increase	1.109	0.951 – 1.292	0.186
GALNT14 genotype, “TT” vs. “TG+GG”	1.423	0.759 – 2.671	0.272
GALNT14 genotype, “GG” vs. “TT+TG”	0.381	0.170 – 0.855	0.019	0.385	0.171 – 0.869	0.022