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. 2016 Oct 27;8(17):29361–29369. doi: 10.18632/oncotarget.12957

Table 2. Association between antiestrogens use and incidence of cervical neoplasia in the breast cancer cohort.

5 year follow-up 10 year follow-up
Low-grade dysplasia High-grade dysplasia High-grade dysplasia ICC
Nonuser AI-included Tamoxifen only Nonuser AI-included Tamoxifen only Nonuser AI-included Tamoxifen only Nonuser AI-included Tamoxifen only
No. of patients 15136 7516 19761 15076 7510 19660 14893 8084 19018 14843 8064 18935
Patients with event 113 33 200 53 27 99 63 30 103 13 10 20
Person-years 49154 26953 66633 49095 26942 66415 60919 38091 79764 60780 38025 79610
Incidence per 105person-years 230 122 300 108 100 149 103 79 129 21 26 25
95% CI 191-276 86.8-172 261-344 82-141 68-146 122-181 80-132 55-112 106-156 12-36 14-48 16-38

HR: hazard ratio;

aModel adjusted for age, Pap smear density and chemotherapy